For years, I've been hand-rolling my own CSS on this and other sites. I ended up getting annoyed with the language and simplifying it down as much as possible.

This week I've been working with Pico CSS and I'm quite impressed. It includes a small, classless CSS file that works well as a minimal base for simple websites. It's heavier than my own hand-rolled CSS but it's very small enough and requires no effort to use. I like it as a starting point for new projects that don't need the complexity of more full-featured CSS frameworks. I can see situations where it may not have enough flexibility but that's just the trade-off for simplicity.